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Commanders vs 49ers Prediction & NFL Odds for Week 16
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Commanders vs 49ers Prediction & NFL Odds for Week 16

by USA WagerDecember 20, 2022

Check out our free Commanders vs 49ers prediction for the NFL week 16 game in Santa Clara. See who USA Wager likes to win and cover the spread in this football game. And, get our insight into the best over-under point total bet.

Commanders vs 49ers Prediction & NFL Odds for Week 16

On Saturday, December 24th, the Washington Commanders travel to take on the San Francisco 49ers at Levi’s Stadium. The two NFC teams will kick things off at 4:05 PM ET, and will be televised on CBS.

Heading into Saturday’s game, San Francisco is the odds on favorite to come away with the win. Will they be able to take care of business at home? Or, does Washington have what it takes to make things interesting? Keep reading to USA Wager’s Commanders vs 49ers prediction.

  • Spread: WAS +7.0 | SF -7.0
  • MoneyLine: WAS +265 | SF -334
  • Total: 39.5

Commanders vs 49ers Prediction: Spread

Heading into this week 16 contest vs San Francisco, the Commanders have an overall record of 7-6-1. This includes going 4-5-1 in the NFC. This season, Washington currently has an average point differential of -0.79 points per game, placing them 16th in the league. So far, the Commanders have been favored in 7 of their 14 games. The average point spread in these matchups is 4.

Across their last 5 road contests, Washington has been good against the spread posting a mark of 4-1. Their overall mark in these games was 4-0-1, while averaging 20.8 points per game. Spanning across their last 5 games as the underdog, Washington has an ATS record of 3-2 while going 3-1-1 straight up.

Heading into this week 16 contest vs Washington, the 49ers have an overall record of 10-4. This includes going 8-2 in the NFC. On the season, San Francisco has one of the better scoring margins in the NFL, ranking 3rd with an average differential of 9.14 points. So far, the 49ers have been favored in 12 of their 14 games. The average point spread in these matchups is -6.

When looking at their past 5 home matchups, San Francisco has an ATS record of 3-2 while averaging 25.2 per game. The team went 4-1 overall in these games. In their last 5 games as the betting favorite, the 49ers have a strong straight up record of 5-0. In addition, their ATS record was 5-0 in these scenarios.

Going into this week’s matchup, we see the best bet being to take the 49ers to come home with a win and cover. Although the team has yet to find their groove on offense ranking just 14th and 9th in passing and rush yards, we see them generating enough production to get the job done.

Free Spread Prediction: San Francisco 49ers -7.0

Commanders vs 49ers Prediction: Total

Heading into this week’s matchup, the Commanders have an over-under record of 4-10. The team’s over-under record has come while averaging just 18.93 points per game, placing them 25th in the league. However, the Washington defense has made things difficult for their opponents, giving up just 19.71 points per contest. On the other side, heading into this week’s matchup, the 49ers have an over-under record of 6-8. For the season, San Francisco has been one of the top performing offenses averaging 24.14 points per contest. In addition, the team has been tough on the other side of the ball, ranking 1st in points allowed.

If looking to place a wager on the over-under, our projections see this game finishing with a total of 41 points, making the over the best bet.

Free Total Prediction: Over 39.5

Check out this post for a full list of our weekly NFL predictions‘>weekly NFL predictions


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