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Cardinals vs Chiefs Prediction & NFL Odds for Week 1

Cardinals vs Chiefs Prediction & NFL Odds for Week 1

by USA WagerSeptember 7, 2022

Check out our free Chiefs vs Cardinals prediction for the NFL week 1 game in Glendale. See who USA Wager likes to win and cover the spread in this football game. And, get our insight into the best over-under point total bet.

Chiefs vs Cardinals Prediction & NFL Odds for Week 1

On Sunday, September 11th, the Kansas City Chiefs travel to take on the Arizona Cardinals at State Farm Stadium. This Non-Conference matchup is set to kickoff at 4:25 PM ET, and will be televised on CBS.

The odds for this game opened with the Kansas City Chiefs as the -2.5 point road favorite. Kansas City opened with a payout of -148 on the moneyline, compared to the current odds of -159. On the other side, Arizona opened by getting 128 on the moneyline. Their current moneyline odds sit at 131.

Heading into Sunday’s game, the odds suggest this will be a close matchup. Will Kansas City pull off the win as a slight road favorite? Or, will Arizona take care of business at home? Keep reading to USA Wager’s Chiefs vs Cardinals prediction.

  • Spread: KC -3.0 | ARI 3.0
  • MoneyLine: KC -159 | ARI 131
  • Total: 53.0

Chiefs vs Cardinals Prediction: Spread

Last season, the Kansas City Chiefs were a below .500 team against the spread, finishing just 8-9-0. The team’s up and down performance vs the spread was disappointing, as they were the betting favorite in 17 of their games.

Similar to their overall ATS record, betting the Kansas City Chiefs on the road provided mixed results as they covered at a rate of 50.0%. In these games, the Kansas City Chiefs had a positive average scoring differential of 7.0 points.

Last season, the Cardinals covered the spread in over half of their games, putting together an ATS record of 10-7-0. The team’s strong performance vs the spread came while being favored in 11 of their games.

Despite the team’s overall success vs the spread, Arizona was less impressive at home, covering at a rate of just 25.0% In these games, the Cardinals had a positive average scoring differential of 11.0 points.

Heading into the game, the Kansas City Chiefs are the betting favorite, with a spread sitting at -3.0. However, look for Kansas City to cover on the road. Even though Kansas City will be facing off against last year’s 11th-ranked scoring defense, the Chiefs finished 2021 with an elite scoring offense, averaging 28.2 points per game.

In particular, the Chiefs should continue last year’s success in the passing game, as the team ranked 12th in completion percentage at 66.4%.

  • Free Spread Prediction: Kansas City Chiefs -3.0


Chiefs vs Cardinals Prediction: Total

Last season, Kansas City had an over-under record of 10-6-1.This week’s betting line of 53.0 is similar to the average over-under line of last year’s team at 51.97 points. But, 59.0% of last year’s games were set higher than this week’s number.

Kansas City accounted for 57.0% of the overall scoring in the 2021-2022 season. This trend includes games that surpassed the over-under betting line, where the Chiefs were responsible for 58.0% of the points.

When playing on the road, the Kansas City Chiefs finished the season averaging 30.62 points per game, right in line with their season average of 28.2. Overall, the team’s defense had its problems on the road, where they allowed 25.75 points per game, compared to their overall figure of 21.41.

Last season, the Arizona Cardinals had an over-under record of 8-9-0.

This week’s betting line of 53.0 is similar to the average over-under line of last year’s team at 48.65 points. However, 88.0% of their contests had betting lines set lower than this week’s figure.

The Cardinals accounted for 55.0% of the overall scoring in the 2021-2022 season. This trend includes games that surpassed the over-under betting line, where the Cardinals were responsible for 53.0% of the points.

When playing at home, the Arizona Cardinals finished the season averaging 22.75 points per game, a slight decrease from their season average of 26.4. Overall, the team’s defense gave up an average of 21.53 points per game, slightly better than their home figure of 24.5.

In this week’s matchup between the Kansas City Chiefs and Arizona Cardinals, look for the two teams to surpass the over-under betting line of 53.0 points. Even though last year’s Cardinals defense held up well against the passing game, Kansas City comes to town with one of the more explosive passing attacks in the NFL, as they finished last year ranked 4th in overall passing yards.

  • Free Total Prediction: Over 53.0

Check out this post for a full list of our weekly NFL predictions

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