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49ers vs Panthers Prediction & NFL Odds For 5
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49ers vs Panthers Prediction & NFL Odds For 5

by USA WagerOctober 5, 2022

Check out our free 49ers vs Panthers prediction for the NFL week 5 game in Charlotte. See who USA Wager likes to win and cover the spread in this football game. And, get our insight into the best over-under point total bet.

49ers vs Panthers Prediction & NFL Odds For Week 5

On Sunday, October 9th, the San Francisco 49ers travel to take on the Carolina Panthers at Bank of America Stadium. The two NFC teams will kick things off at 4:05 PM ET, and will be televised on CBS.

Heading into Sunday’s game, San Francisco is a strong favorite to come away with the win. But, can Carolina take advantage of playing at home and pull off the upset? Keep reading to USA Wager’s 49ers vs Panthers prediction.

  • Spread: SF -6.5 | CAR +6.5
  • MoneyLine: SF +-276 | CAR 224
  • Total: 39.0

49ers vs Panthers Prediction: Spread

Heading into this week 5 contest vs Carolina, the 49ers have an overall record of 2-2. This includes going 2-1 in the NFC. On the season, San Francisco has one of the better scoring margins in the NFL, ranking 5th with an average differential of 6.25 points. Through 4 games, the 49ers have been the favorite in every contest. Currently, their average point spread is -4.

In their last 5 games away from home, the 49ers have a straight up record of 2-3-0 while going 3-2 vs the spread. The team’s offense averaged 14.6 points per game in these contests. In their last 5 games as the betting favorite, the 49ers have a straight up record of 3-2 and an ATS mark of 3-2.

Heading into this week 5 contest vs San Francisco, the Panthers have an overall record of 1-3. This includes going 1-2 in the NFC. This season, Carolina currently has an average point differential of -1.75 points per game, placing them 19th in the league. Coming into this week’s action, the Panthers will be the betting underdog for just the 2nd time this year. In the only other game as the underdog, the point spread was 2 points.

Through their last 5 home games, Carolina has an ATS record of just 1-4. However, their overall record was 1-4 while averaging 17.8 points per game. The Panthers have a straight up record of 1-4 in their previous 5 games as the underdog. Against the spread, they had a mark of 1-4.

Going into this week’s matchup, we see the best bet being to take the Panthers to come away with a win and cover. Although the team has yet to find their groove on offense ranking just 30th and 24th in passing and rush yards, we see them generating enough production to get the job done.

Free Spread Prediction: Carolina Panthers 6.5

49ers vs Panthers Prediction: Total

Through 4 games, the 49ers have yet to have a game surpass an over-under betting line, posting an OU mark of 0-4. The team’s over-under record has come while averaging just 17.75 points per game, placing them 28th in the league. However, the San Francisco defense has made things difficult for their opponents, giving up just 11.5 points per contest. On the other side, heading into this week’s matchup, the Panthers have an over-under record of 1-3. This season, the Panthers are averaging 19.5 points per contest, placing them 17th in the league. Defensively, the team is ranked just 13th in points allowed per game.

In this week’s matchup, we see the 49ers and Panthers combining for 32 points, leading us to recommend taking the under.

Free Total Prediction: Under 39.0

Check out this post for a full list of our weekly NFL predictions‘>weekly NFL predictions


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