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Duke vs Pittsburgh Prediction & College Football Odds for Week 10
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Duke vs Pittsburgh Prediction & College Football Odds for Week 10

by Mason AsherNovember 1, 2021
  • Pittsburgh will gain 600 yards of offense
  • Duke will run for more than 150 yards
  • Both teams will score 24 or more points

The Duke Blue Devils play host to the Pittsburgh Panthers as they square off in a Saturday afternoon matchup. Pittsburgh is 6-2 on the season and is coming off a heartbreaking loss to the Miami Hurricanes. Duke sits at 3-5 on the season and have lost four games in a row. Both of these teams are looking at this game as a very important one on the schedule.

Despite losing four games in a row, Duke could still make their way into a bowl game. They will need to secure a win this week to have a shot at that. Pittsburgh still has an outside shot at making the ACC Championship and will need to not stumble for the rest of the year. There is a lot riding on this game for both teams which will make this a fun game.

Betting Odds & Lines for This Game

  • Spread: Pittsburgh -20.5 (-110) / Duke +20.5 (-110)
  • MoneyLine: Pittsburgh -1250 / Duke +750
  • Total: Over 64 points (-110) / Under 64 points (-110)
  • All odds listed are courtesy of (PointsBet | Caesars | DraftKings | Fanduel | BetRivers)

Duke vs Pittsburgh Prediction: Spread

Pittsburgh has been rolling on offense this season and have been consistently putting up points. They are averaging 43.9 points a game this year and have put up 27 points or more in each game this year. Duke’s defense allows a ton of points and have allowed 45 or more in their last two games. Pittsburgh should roll to a cover.

  • Free Prediction: Pittsburgh -20.5

Duke vs Pittsburgh Prediction: MoneyLine

There is not a ton of value in this moneyline no matter how you look at it. Pittsburgh is almost a sure lock to win the game and Duke’s moneyline just isn’t that high. If you are going to bet a moneyline take Pittsburgh.

  • Free Prediction: Pittsburgh -1250

Pittsburgh vs Duke Prediction: Total

Pittsburgh has scored a ton of points this year and Duke has not. Duke is averaging 24.5 points a game and have been held to seven total points over the last two weeks. Look for Pittsburgh to continue their offensive dominance and for Duke to find the endzone multiple times this weekend. Take the over.

  • Free Prediction: Over 64 points

Bet on This College Football Game


Check out this post for a full list of our weekly college football predictions.

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About The Author
Mason Asher