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49ers vs Rams Prediction & NFL Odds For Week 4

49ers vs Rams Prediction & NFL Odds For Week 4

by USA WagerSeptember 29, 2022

Check out our free Rams vs 49ers prediction for the NFL week 4 game in Santa Clara. See who USA Wager likes to win and cover the spread in this football game. And, get our insight into the best over-under point total bet.

Rams vs 49ers Prediction & NFL Odds for Week 4

On Monday, October 3rd, the Los Angeles Rams travel to take on the San Francisco 49ers at Levi’s Stadium. This NFC West showdown has a kickoff time set for 8:15 PM ET, and will be televised on ESPN.

Heading into Monday’s game, the odds suggest this will be a close matchup, with San Francisco getting a slight edge on the spread. However, Los Angeles will head to Levi’s Stadium looking to pull off a road upset. Keep reading to USA Wager’s Rams vs 49ers prediction.

  • Spread: LAR +1.5 | SF -1.5
  • MoneyLine: LAR 101 | SF +-120
  • Total: 42.5


Rams vs 49ers Prediction: Spread

Going into week 4, Los Angeles has a record of 1-0 in the NFC West. Overall, the Rams head into action with a record of 2-1. This season, Los Angeles currently has an average point differential of -3.0 points per game, placing them 20th in the league. Coming into this week’s action, the Rams will be the betting underdog for just the 2nd time this year. In the only other game as the underdog, the point spread was 1.5 points.

When looking at their past 5 road matchups, Los Angeles has an ATS record of 3-2 while averaging 24.6 per game. The team went 5-0-0 overall in these games. In their last 5 games as the underdog, Los Angeles has gone 3-2 vs the spread. Straight up, the team went 3-2 in these matchups.

Going into week 4, San Francisco has a record of 1-0 in the NFC West. Overall, the 49ers head into action with a record of 1-2. On the season, San Francisco has one of the better scoring margins in the NFL, ranking 9th with an average differential of 3.33 points. Through 3 games, the 49ers have been the favorite in every contest. Currently, their average point spread is (-5.5, 2).

When looking at their past 5 home matchups, San Francisco has an ATS record of 5-0 while averaging 29.2 per game. The team went 5-0 overall in these games. Looking back on the team’s last 5 games as the favorite, the 49ers have a straight up record 2-3. Their record vs the spread in these games was 2-3.

This week, our projections point to the Rams covering the spread in their matchup vs San Francisco. Although the team is far from a prolific passing offense, we see them performing well in week 4.

Free Spread Prediction: Los Angeles Rams 1.5

Rams vs 49ers Prediction: Total

Heading into this week’s matchup, the Rams have an over-under record of 1-2. This season, the Rams are averaging 20.33 points per contest, placing them 15th in the league. Defensively, the team is ranked just 21st in points allowed per game. On the other side, through 3 games, the 49ers have yet to have a game surpass an over-under betting line, posting an OU mark of 0-3. The team’s over-under record has come while averaging just 15.67 points per game, placing them 29th in the league. However, the San Francisco has made things difficult for their opponents, giving up just 12.33 points per contest.

If looking to place a wager on the over-under, our projections see this game finishing with a total of 46 points, making the over the best bet.

Free Total Prediction: Over 42.5


Check out this post for a full list of our weekly NFL predictions

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