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Giants vs Cardinals Prediction & NFL Odds for Week 2

73.5 Million Americans Plan to Bet on Football

by USA WagerSeptember 13, 2023

At 4:05 ET on Sunday, September 17th, the Giants travel to take on the Cardinals. This NFL week 2 matchup will take place at State Farm Stadium in Glendale with FOX carrying television coverage.

In this NFC matchup, the Giants are heading in as 6 point road favorites. Will they manage to win on the road and cover?

Prediction at a Glance for Cardinals vs Giants

The value is there for the Cardinals at +6.
Giants over Cardinals straight-up.
Take the under at 39.5 now while you still can.

Betting Odds & Lines for this Game

Spread: Giants -6 | Cardinals +6
Total: 39.5
MoneyLine: Giants -237 | Cardinals +195

All Odds are courtesy of (BetMGM | DraftKings | Fanduel | BetRivers)

Giants vs. Cardinals Prediction: Spread

Over their last three regular season games, the Giants have gone 1-2 straight up. Across these games, their ATS record was just 1-2, while posting an over-under record of 1-2. New York has a 2-3 record in their last five road games. In this stretch, they averaged 19 points per game while allowing 24. The team’s also performed well vs the spread at 4-1.

The Cardinals have gone 0-3 over their last three regular season games. They have held up well vs the spread in these matchups, going 2-1 as well as an over-under record of 1-2. Across their last five home contests, Arizona has a 3-2 record vs the spread. Their overall mark in these games was 1-4, while averaging 18 points per game.

Even though the Giants are favored by 6 vs. the Cardinals, I don’t like how they got off to a slow start in the first half of their previous game. Look for the Cardinals to cover (+6).

Free Spread Prediction Cardinals +6 (Bet Now)

Giants vs. Cardinals Prediction: MoneyLine

To start their season, the Giants played an away game against the Eagles, but they ended up with a 22-16 loss. They head into week two at 0-1. Davis Webb wrapped up the game with 168 passing yards and a passer rating of 75. Overall, he completed 23 of 40 passes.

In their season opener, the Cardinals had an away game against the 49ers, resulting in a 38-13 loss. They enter week two with a 0-1 record. For the game, quarterback David Blough attempted 18 passes and finished with 14 completions for 180. His passer rating for the game was 87.

Even though the Giants are favored by 6 vs. the Cardinals, I don’t like how they got off to a slow start in the first half of their previous game. Look for the Cardinals to cover (+6).

Free MoneyLine Prediction Giants -237 (Bet Now)

Giants vs. Cardinals Prediction: Total

After combining with the Eagles for 38 points, the Giants have started of their season with an over/under record of 0-1. The over/under line going into the game was 42.5.

Their first game of the season finished with 51 points, which was 10th in the league for the opening week. Their over/under record to start the season is 0-1.

All of Arizona’s games have had over/under lines lower than this week’s line of 39.5. We see this line being set to high for these teams, my pick is on the under.